The Peyronie disease and Canada healthcare pharmacy

This disease has been described by Peyronie in 1743, its incidence situates between thirty five and sixty years old. The symptoms of the disease consist in the apparition of nodules or indurated plaques of the penis, more frequently situated in the dorsal or lateral region, but which can also appear at the root of the cavernous bodies or close to the gland. In the beginning, the induration appears like a unique nodule or multiple of high consistency, and then like some cartilaginous plaques which in time, during the evolution, unite. In some cases, also produce calcifications at the level of the indurations, giving them a bony consistence. 

Because of these histopathological modifications, the patients accuse pains and deformations of the penis during the erection and difficulties of copulation because of the penis’s angle. The curving of the penis can be dorsal, lateral or ventral. The pain appears because of the traction over the penian indurated tissue during the erection. Canadian health care mall – best website to order discount viagra medications.

The sexual disorders that the Peyronie disease causes consist in the apparition of painful erections or very painful (the first symptom that is noticed by these sick persons) followed by an incurvation of the penis during the erection that causes difficulties, sometimes, with the impossibility of doing the sexual act. Because of the difficulties that appear in copulation, these sick persons become bad-tempered, agitated, anxious and through the evolution of the disease can get to sexual impotence of mixed nature, lesional and psychogenic.

The induration is situated in the beginning in albuginea, then extends to the cavernous bodies usually and much rarer the spongious body of the urethra. From a histopathological point of view, C. G. Dimitriu and his coworkers had shown that in the beginning it is produced a mucoid degeneration, then a process of sclerosis that contains also the fundamental substance, so that in the following to produce a very intense hyalinization of the conjunctive tissue that appears very thin in vessels.

Looking at the etiopathogeny of the diseases, it has been incriminated so far, one of a time, the following factors: lues, lymphogranulomatosis, gout, and diabetes. Touraine considers it to be a polifibromatosis, because the disease is associated with the Dupuytren disease (the retraction of the palmary aponeurosis). But some authors have found that this association is rare: only two in thirty two cases presented the Dupuytren disease in the statistics of C. Noaghea and his coworkers. Other authors like: Vert, Schelle and Vessin consider that the Peyronie disease is produced by micro-traumatisms of the penis, repeated, during the sexual act.

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