Priligy (Dapoxetine) vs Viagra Super Force vs Malegra DXT

Very often men use the word impotency to tell about the insufficient ability in intimate sphere. But nowadays therapists do not use this term. National Institute of Public Health in U.S. suggested substituting this word into “erectile dysfunction”. This term is utilized widely and means not only disorder to ED, but also a number of other symptoms including orgasm failure or weakening of sexual attraction. There are two types of erectile dysfunction: initial and secondary. In case a man is not able to commit a fully-realized sexual intercourse at no time, it is called congenital or primary dysfunction.

The most widespread type is secondary, when a man had a normal sexual life but then due to several factors he appeared to have erectile disorders.  The most frequent complaints are about insufficient erection because of which natural coitus is impossible. Or vice versa, excessively strong erection disappears after the attempt of first sexual intercourse. Along with ED treating medications men all around the globe breathed a sigh of relief. Let us examine and compare the outstanding representatives of this group which have similar features and some differences: Malegra DXT, Priligy and Viagra Super Force.

Composition and Presentation Form

• Priligy is a synonym of dapoxetine containing 30 or 60 mg of this main substance. It is represented by a coated tablet of grey color.
• Viagra Super Force has two main substances: sildenafil citrate 100mg and dapoxetine 60mg. It is also in the tableted form.
• Malegra DXT combines two active substances: sildenafil citrate (100mg) and duloxetine (30mg).

What are these substances responsible for?

Dapoxetine is a selective serotonin reuptake inhibitor (SSRI) of short action. Its clinical trials have demonstrated that it prevents effectively from premature ejaculation among men above 18 years of age. According to statistics, one third of menfolks of all age groups beginning from 18 years suffer from PE and incapacity to retain a long-term erection during sexual intercourse. Dapoxetine helps to prolong coitus in average by three-four times. SSRI blocks ejaculation by arresting receptors and absorbing serotonin in cerebrum.

Sildenafil is a well-known phosphodiesterase type 5 inhibitor. It is a constituent part of renowned Viagra. It contributes to increase of blood stream to pelvic organs, relaxation of smooth muscle cells and enhancement of erection.

Duloxetine is not so well known, but among those who have tried a lot of various ED treatment drugs, it is quite popular. It inhibits serotonin and norepinephrine reuptake which results in increased serotonergic and noradrenergic neurotransmission in central nervous system. Duloxetine has a central mechanism of inhibition of pain syndrome which is first of all is manifested by increasing of pain threshold in case of pain syndrome of neuropathic etiology. There are several medicines based on duloxetine which are helpful in struggling against stresses and depression.

Indications for Usage

Priligy is highly efficient in treatment of premature ejaculation, whereas Viagra Super Force and Malegra DXT are of double action due to the presence of two main ingredients in their composition. These two are unique remedies combining the effects for ED and PE therapy at a time. In Viagra Super Force and Malegra DXT there is a combination of dapoxetine + sildenafil and duloxetine + sildenafil accordingly. The combination of such ingredients will restore the erectile function and normalize and slow down the emission of seminal fluid. Moreover, many men will experience the solidified effect.

Posology and Method of Administration

Priligy

Priligy is designed for peroral use. The tablet should be taken with a lot of water regardless of food acceptance. Recommended initial dosage for all men is 30mg. This dose is taken 1-3 hours before planned sexual intercourse. In case of insufficient effect and well tolerability of the dosage of 30mg, it may be enhanced up to 60mg. Maximum daily dose is once per day.

Viagra Super Force

Initial dose of the product varies from 25 to 100mg per day. Medical experts recommend taking Viagra Super Force 1-3 hours before expected coitus. The medication falls into the category of medicinal products. It acts within 4-5 hours. The effect may be expected in 40 minutes after its intake. Tablets are of slightly bitter taste. They are prohibited to be taken along with alcohol.

Malegra DXT

This medication is taken 1 tablet 20-40 minutes before sex. It should be borne in mind that it is absolutely incompatible with alcohol. Therefore, combination with even small doses of alcoholic beverages is inadmissible. Energy food with high content of lipids (such as hamburger, hot dog, etc.) may slow down the time of effect occurrence considerably. The action lasts 4-6 hours.

Counter-indications

Although Viagra Super Force and Malegra DXT are quite strong remedies combining two main functions useful for male health: premature ejaculation and erectile dysfunction treatment, they have the enhanced number of contraindications. Their number duplicates due to the presence of two main components. In this case, Priligy has the most beneficial position. Let us examine the contraindications of each active substances: dapoxetine, sildenafil, duloxetine.

The most common among them are the following:

• hypersensitivity to dapoxetine, sildenafil, duloxetine or any auxiliary agent of the drug.
• Pronounced cardiac disorders (II-IV class cardiac failure, cardiac conduction disorder, tachybradycardia syndrome, in case of absence of constant cardiostimulator, coronary artery disease, or cardiac valve disease).
• Simultaneous intake with monoamine oxidase inhibitors within 14 days after their intake termination.
• Co-administration with thioridazine within 14 days after their intake termination.
• Combination with serotonin reuptake inhibitors and other drugs having serotonergic action within 14 days after their intake termination.
• Co-administration with CYP3A4 active inhibitors, such as nefazodone, ketoconazole, atazanavir, itraconasole, nelfinavir, ritonavir, sacvinavir, telithromycin.
• Malegra DXT and Viagra Super Force are not to be combined with some antibiotics, nitrate-containing medications, alpha blockers, beta blockers, HIV protease inhibitors.
• Mild and severe hepatic disorders.
• Severe renal diseases.
• Under-age.
• Lactose intolerance.
• Penis deformation.
• Heart or apoplectic attack within the last six months.
• Erythroid myeloma.
• Primary pigmentary degeneration of retina.

Side-Effects

In this case the story repeats: Viagra Super Force and Malegra DXT  have enhanced number of adverse effects, since they combine two active substances. Side-effects may be more pronounced after usage of these two medicines in comparison with Priligy.

Priligy

In clinical trials there were registered the following side-effects which appeared to be dose-dependent: nausea, vertigo, headache, diarrhea, insomnia, low energy, weakness.

Viagra Super Force

This remedy is generally well tolerated. In some cases a patient may experience headache, blushing of face and upper part of body, nausea, diarrhea, swollen mucosa of nasal cavity, dyspepsia.

Malegra DXT

Malegra is distinguished by rare cases of adverse effects. If they occur, they are manifested in the following forms: blushing, nausea, headache, stuffiness in nose, vertigo.