In order to be healthy, one shall know when to go to bed and when to get up. When you go to bed on time, your body will rest, and your spirit will study. The sleep is the physioastral life on the Earth. Eating is just the physical life on the Earth. Work is the […]
The exercise is used for adjusting the front part of the brain. II exercise. This exercise is like the first one, but the left arm is raised up under an angle of 45° from the shoulder level and the right one is to be let down under the same angle, at which you squat six […]
Impotence In any relationship, a male sexual impotence can take place at some time or other in all relationships. When this happens it not only affects the man, but also the woman feels distress. Yes, impotence can deprive the wife of sexual plea- sure and cause personal and psychological distress as well. The good news […]
What Are the Complications of Raised Blood Pressure? For many years raised blood pressure may cause no symptoms. Occasionally, raised blood pressure can be associated with headaches and nose bleeds, but usually only when the blood pressure is very high. However, high blood pressure makes the heart and arteries work harder, causing damage over the […]
Soon after the approval of sildenafil for treatment of ED, several reports of adverse events temporarily related to use of sildenafil raised concerns regarding the safety of PDE-5 inhibitors, particularly in patients with cardiovascular disease. However, detailed statistical analyses, considering that the patient population using these agents is characterized by a high prevalence of cardiovascular […]
There is another class of agents requiring special attention: α-blockers (e.g., doxazosin, terazosin, or tamsulosin) used as antihypertensive agents or in the treatment of benign prostate hyperplasia because of potential enhancement of blood pressure-lowering effects. For vardenafil, tadalfil, and sildenafil, the label precaution is used for a combination with α-blockers—especially with higher doses. No more […]
Because smooth muscle cells of both the arterial and venous system contain significant amounts of PDE-5, blood pressure-lowering effects of the three agents are especially important. In a study by Zusman et al. oral administration of sildenafil resulted in a non-dose-dependent reduction of arterial systolic and diastolic blood pressure of 7 to 10 mmHg. These […]
For the physician interested in cardiovascular issues, PDE-5 inhibitors, now broadly used for the treatment of ED, are a highly interesting class of agents. Sildenafil, the first available agent for treatment of ED, was initially developed to find a novel anti-anginal concept. Although its anti-anginal potency was not promising in the first clinical studies, the […]
A detailed medical history, including sexual and psychosocial history and an updated list of the medications, should be obtained from any patient seeking help for ED. As mentioned earlier, because of the close association between cardiovascular risk factors and ED, searching for potential cardiovascular disorders in these patients appears worth-while. In some cases, ED may […]
ED is highly prevalent among men, regardless of geography or ethnicity. Its prevalence and incidence are associated with aging, cardiovascular disease, diabetes, hyperlipid-emia, lifestyle issues (such as smoking, alcohol abuse, obesity, and sedentary lifestyle), depression, pelvic surgery, neurological disorders, trauma, symptoms of benign prosta-tic hyperplasia, side effects from medication, and psychological and interpersonal factors. The […]
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